Manchester United lost 3-2 against Galatasaray at Old Trafford on Tuesday, while Lens defeated Arsenal 2-1.
Rasmus Hojlund scored a brace for the Red Devils, while Wilfred Zaha, Muhammed Akturkoglu and Mauro Icardi also found the back of the net for the visitors.
Lens rallied to beat Arsenal 2-1 at the Stade Bollaert-Delelis in another fixture.
Gabriel Jesus gave Arsenal the lead on 14 minutes but Lens won the game through Adrien Thomasson and Elye Wahi strikes.
Real Madrid also defeated Napoli 3-2 at the Maradona stadium in Italy.
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